Treatment corrects severe insulin imbalance in animal studies

Courtesy EurekAlert! - Medicine and Health  Wed, 07/30/2008 - 23:00

(Children's Hospital of Philadelphia) Researchers have used a drug to achieve normal levels of blood sugar in animals genetically engineered to have abnormally high insulin levels.

If this approach succeeds in humans, it could become an innovative medicine for children with congenital hyperinsulinism, a rare but potentially devastating genetic disease in which insulin levels become dangerously high.

There is currently no effective medical treatment for children with the most common type of congenital hyperinsulinism.

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