(Burnham Institute) Investigators at Burnham Institute for Medical Research, UBC and UCSD have found that normal synaptic activity in nerve cells protects the brain from the misfolded proteins associated with Huntington's disease.
They also found that the drug Memantine, which is approved to treat Alzheimer's disease, successfully treated Huntington's disease in a mouse model by preserving normal synaptic electrical activity and suppressing excessive extrasynaptic electrical activity.
The Burnham buzz
(Burnham Institute) Contained in this release are recent developments at the Burnham Institute for Medical Research inNovember 2009.
How proteins talk to each other
(Burnham Institute) Investigators at Burnham Institute for Medical Research have identified novel cleavage sites for the enzyme caspase-3 (an enzyme that proteolytically cleaves target...
Reactive oxygen's role in metastasis
(Burnham Institute) Researchers at the Burnham Institute for Medical Research have discovered that reactive oxygen species, such as superoxide and hydrogen peroxide, play a key role in...
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