Researchers discover brain tumor's 'grow-or-go' switch

Courtesy EurekAlert! - Cancer  Wed, 03/10/2010 - 23:00

(Ohio State University Medical Center) High energy levels cause glioblastoma cells to proliferate; low levels cause them to grow less and to migrate.

This study discovered that a molecule called miR-451 coordinates this grow-or-go behavior, which is closely linked to the cells' ability to invade and spread.

Thus, the molecule might be a biomarker for predicting survival in patients with glioblastoma multiforme and may serve as a target to develop drugs to fight these tumors.

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