whitehead institute for biomedical research

New model tracks the immune response to a T

EurekAlert! - Infectious and Emerging Diseases  Wed, 04/07/2010 - 22:00

(Whitehead Institute for Biomedical Research) Whitehead researchers have created novel mouse models of the immune system starting with T cells primed for the infectious disease toxoplasmosis by generating cloned mice from these T cells.

This type of model more accurately represents how immune cells respond to infectious diseases, and could be used to more reliably study immune cell biology and the role of immune cells in infectious disease.

Earlier immune system models are inherently limited by the laboratory procedure involved.


 

The ends of mRNAs may prevent the beginnings of cancer

EurekAlert! - Cancer  Wed, 08/19/2009 - 22:00

(Whitehead Institute for Biomedical Research) The tail end of a cell's protein templates may contain important cues that control protein creation.

When this section is lopped off of a template, a cell can make too many copies of that protein and turn a normal cell cancerous, according to Whitehead Institute scientists.