university cancer researchers

Marker identifies breast cancer patients likely to respond to ta...

EurekAlert! - Cancer  Tue, 05/17/2011 - 22:00

(Thomas Jefferson University) Cancer researchers at the Kimmel Cancer Center at Jefferson and an international team of collaborators have discovered a biomarker in breast cancer that may help identify which women will respond to anti-estrogen therapy.


 

Microbubble-delivered combination therapy eradicates prostate ca...

EurekAlert! - Cancer  Mon, 05/09/2011 - 22:00

(Virginia Commonwealth University) Cancer researchers are a step closer to finding a cure for advanced prostate cancer after effectively combining an anti-cancer drug with a viral gene therapy in vivo using novel ultrasound-targeted microbubble-destruction (UTMD) technology.


 

Gene therapy for metastatic melanoma in mice produces complete r...

EurekAlert! - Cancer  Wed, 11/17/2010 - 23:00

(Indiana University School of Medicine) Indiana University cancer researchers report a potent anti-tumor gene introduced into mice with metastatic melanoma has resulted in permanent immune reconfiguration and produced a complete remission of their cancer


 

Early immune response needed for hit-and-hide cancer viruses

EurekAlert! - Medicine and Health  Wed, 01/13/2010 - 23:00

(Ohio State University Medical Center) Human retroviral infections might be more manageable if the immune system could respond strongly to the virus early, say Ohio State University cancer researchers in a new study.

The research examined the retrovirus HTLV-1, which causes adult T-cell leukemia. It indicates that if the immune system could kill virus-infected cells within days of infection, it may inhibit the virus's ability to establish reservoirs of infected cells and make the infection more treatable later.


 

Tumor-attacking virus strikes with 'one-two punch'

EurekAlert! - Cancer  Mon, 11/30/2009 - 23:00

(Ohio State University Medical Center) Ohio State University cancer researchers developed a tumor-attacking virus that kills brain-tumor cells and blocks tumor blood-vessel growth.

The research shows that viruses designed to kill cancer cells -- oncolytic viruses -- might be more effective against aggressive brain tumors if they can also inhibit blood-vessel growth.

The study showed that an oncolytic virus containing the gene for this protein, called vasculostatin, eliminated human glioblastoma tumors growing in some animals and significantly slowed tumor recurrence in others.


 

Breast cancer intervention reduces depression, inflammation

EurekAlert! - Cancer  Sun, 08/30/2009 - 22:00

(Ohio State University Medical Center) A psychological intervention for newly diagnosed breast cancer patients with symptoms of depression both relieves patients' depression and lowers indicators of inflammation in the blood.

The new study by Ohio State University cancer researchers involves patients with stage II or III breast cancer.

Patients who received a psychological therapy that reduced stress and enhanced their ability to cope experienced significant relief of depressive symptoms, followed by a reduction in markers of inflammation.


 

Targeting tumor behavior may lead to new liver cancer drugs

EurekAlert! - Cancer  Wed, 06/17/2009 - 22:00

(Ohio State University Medical Center) Ohio State University cancer researchers used computational and genomic methods to identify possible anti-cancer agents that target multiple genes simultaneously.

The researchers were seeking agents that might reverse gene changes in invasive liver cancer cells and block the spread of the disease in the body.

The strategy is a new way to find potentially useful anti-cancer agents because it identifies agents that strike multiple targets involved in a particular stage of disease development.