investigational protease inhibitor

EASL: Boceprevir Plays Well With Interferon Drugs (CME/CE)

MedPage Today Infectious Disease  Sat, 04/02/2011 - 09:00

BERLIN (MedPage Today) -- Boceprevir, an investigational protease inhibitor for hepatitis C virus (HCV) infection, is effective against genotype 1 of the virus irrespective of whether it is combined with peginterferon alfa-2a or 2b.


 

AASLD: Six Months of Novel Agent Works in Hep C (CME/CE)

MedPage Today Infectious Disease  Tue, 11/02/2010 - 11:23

BOSTON (MedPage Today) -- A shorter, six-month course of the investigational protease inhibitor boceprevir added to standard combination treatment appears just as effective as almost a full year of therapy for patients with a challenging subtype of hepatitis C, researchers reported here.


 

Novel HCV Drug Can Double Response Rate (CME/CE)

MedPage Today Infectious Disease  Sun, 08/08/2010 - 16:30

(MedPage Today) -- An investigational protease inhibitor aimed at blocking hepatitis C replication can double the response rate compared with standard care, researchers said.


 

DDW: Telaprevir Said to Benefit Hardest HCV Cases (CME/CE)

MedPage Today Infectious Disease  Sat, 05/08/2010 - 06:34

NEW ORLEANS (MedPage Today) -- Adding an investigational protease inhibitor for hepatitis C virus (HCV) to standard treatment induced rapid and sustained virologic responses in many patients with poor responses to standard therapy alone, researchers said here.


 

Telaprevir Raises Response Rates in Hepatitis C (CME/CE)

MedPage Today Infectious Disease  Wed, 04/07/2010 - 15:00

Re-treating hepatitis C patients with standard therapy plus the investigational protease inhibitor telaprevir significantly improved the chances of eradicating the virus, researchers found.


 

DDW: Telaprevir Improves HCV Clearance in Resistant Patients (CM...

MedPage Today Infectious Disease  Wed, 06/03/2009 - 10:19

CHICAGO (MedPage Today) -- The investigational protease inhibitor telaprevir, added to standard hepatitis C (HCV) treatment, produced a sustained virologic response in about half of patients who had previously failed with conventional therapy, a phase IIb trial showed.


 

Sustained Response Seen with New Hepatitis C Drug

MedPage Today Infectious Disease  Fri, 04/24/2009 - 13:24

WHEELING, W.Va. (MedPage Today) -- An investigational protease inhibitor for hepatitis C virus (HCV) infection showed promise in a phase II trial as add-on therapy, a researcher said.


 

CROI: Investigational Drugs May Give Ritonavir Competition

MedPage Today Infectious Disease  Tue, 02/10/2009 - 15:44

MONTREAL (MedPage Today) -- Data presented here on two investigational protease inhibitor boosters have encouraged HIV clinicians who have been relying solely on ritonavir (Norvir).