inflammatory bowel disease

Inflammatory cues modulate goblet cell products important for in...

EurekAlert! - Medicine and Health  Thu, 12/01/2011 - 23:00

(Society for Experimental Biology and Medicine) The paper by Croix and coauthors demonstrates that both microbial and host inflammatory factors modulate sulfomucin production in the human goblet cell line.

Sulfomucins provide crucial protection to the intestinal mucosa and their expression is altered in mucosal lesions of both inflammatory bowel disease and colorectal cancer.

The present data demonstrate for the first time that the Golgi sulfotransferases responsible for mucin sulfation are highly sensitive to inflammatory cues.


 

Lab Notes: Vaccine May Keep Rabies, Ebola at Bay

MedPage Today Infectious Disease  Fri, 08/26/2011 - 15:00

(MedPage Today) -- Rabies viruses engineered to include an Ebola virus antigen protected against both diseases in mouse models.

Also in this week's Lab Notes, researchers found a new member of the interleukin protein family that may shut down inflammatory bowel disease.


 

Comorbidities Tied to Postop Risk of Death in IBD (CME/CE)

MedPage Today Surgery  Tue, 08/16/2011 - 07:00

(MedPage Today) -- Among patients with inflammatory bowel disease who are undergoing bowel surgery, the likelihood of dying in the hospital increases the more comorbidities they have, researchers found.


 

C. difficile increases risk of death 6-fold in patients with inf...

EurekAlert! - Infectious and Emerging Diseases  Mon, 04/18/2011 - 22:00

(Imperial College London) Patients admitted to hospital with inflammatory bowel disease face a sixfold greater risk of death if they become infected with Clostridium difficile, a new study has found.


 

Digestive experts grade treatment options for inflammatory bowel...

EurekAlert! - Medicine and Health  Thu, 04/07/2011 - 22:00

(American College of Gastroenterology) The American College of Gastroenterology published a new evidence-based systematic review on the management of Inflammatory Bowel Disease (IBD) as a supplement to The American Journal of Gastroenterology for April 2011, a special issue entirely dedicated to IBD.

This clinical monograph, based on a comprehensive meta-analysis, offers new graded recommendations on medical management of IBD, a chronic digestive disorder which includes Crohn's disease and ulcerative colitis.


 

Inflammatory Bowel Disease Raises Clot Risk

WebMD Health  Tue, 02/22/2011 - 13:38

Inflammatory bowel disease may more than double the risk of a serious blood clot in the legs or lungs, according to a new study.


 

Researchers discover new signaling pathway linked to inflammator...

EurekAlert! - Medicine and Health  Mon, 12/13/2010 - 23:00

(University of California - San Diego) Scientists at the University of California, San Diego School of Medicine have described for the first time a key inhibitory role for the IL-1 signaling pathway in the human innate immune system, providing novel insights into human inflammatory bowel disease (IBD) and potential new treatments.


 

Immune system changes linked to inflammatory bowel disease revea...

EurekAlert! - Medicine and Health  Wed, 12/08/2010 - 23:00

(Virginia Tech) Scientists at the Virginia Bioinformatics Institute at Virginia Tech have discovered some of the key molecular events in the immune system that contribute to inflammatory bowel disease.


 

Study Asks Adolescents With Inflammatory Bowel Disease About Use...

NCCAM Featured Content  Tue, 06/15/2010 - 08:07

Many adolescents with inflammatory bowel disease are currently using or would consider using complementary and alternative medicine (CAM)—specifically mind-body therapies such as relaxation and guided imagery—to help manage their symptoms, according to a study published in the journal Inflammatory Bowel Disease.

This disease is actually a group of disorders (including Crohn's disease and ulcerative colitis) that cause inflammation of the intestines.


 

Drugs, surgery are treatments for ulcerative colitis

NYDailyNews.com - Health - NY Daily News  Tue, 03/16/2010 - 13:53

Ulcerative colitis is a form of inflammatory bowel disease that can be extremely disabling, and tends to affect younger people.