human cells

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Blocking cancer in its path: New cellular defect discovered

EurekAlert! - Medicine and Health  Mon, 03/15/2010 - 23:00

(University of California - San Francisco) UCSF researchers have discovered that a key cellular defect that disturbs the production of proteins in human cells can lead to cancer susceptibility.

The scientists also found that a new generation of inhibitory drugs offers promise in correcting this defect.


 

New discovery reveals fate of nanoparticles in human cells

EurekAlert! - Medicine and Health  Mon, 09/21/2009 - 22:00

(Biotechnology and Biological Sciences Research Council) Scientists have uncovered what happens to biomimetic nanoparticles when they enter human cells.

They found that the important proteins that make up the outer layer of these nanoparticles are degraded by an enzyme called cathepsin L.

Scientists now have to take this phenomenon into account and overcome this process to ensure the exciting field of nanomedicine can progress.


 

Researchers identify potential new avenue to attack cancer

EurekAlert! - Cancer  Tue, 08/11/2009 - 22:00

(Michigan State University) New insight into how human cells reproduce could help scientists move closer to finding an "off switch" for cancer.

Cancer cells divide uncontrollably and can move from one part of the body to another. They undergo dramatic shifts in shape when they do so, said Aaron DeWard, an MSU cell and molecular biology doctoral candidate.

He's trying to figure out how certain proteins trigger cell movement and division and how cancer hijacks the system to create genomic instability.


 

Human cells secrete cancer-killing protein, UK study finds

EurekAlert! - Cancer  Wed, 07/22/2009 - 22:00

(University of Kentucky) The tumor-suppressor protein Par-4 is secreted by human and rodent cells and activates a novel extrinsic pathway involving cell surface GRP78 receptor for induction of apoptosis, researchers at the University of Kentucky led by Vivek Rangnekar announced in Cell.