chemoprevention

(University of Oklahoma) Cancer researchers at the Peggy and Charles Stephenson Oklahoma Cancer Center have found a way to stop early stage pancreatic cancer in research models -- a result that has far-reaching implications in chemoprevention for high-risk patients.

(World Journal of Gastroenterology) Helicobacter pylori has been accepted as an important pathogen inducing gastric cancer.

A research group from Taiwan investigated optimal intervention point of Celecoxib, to inhibit H. pylori-associated gastric carcinogenesis in Mongolian gerbils.

They found that short-term use resulted in less severe inflammation and inhibited the invasion degree of gastric cancer.

Therefore, Celecoxib could be used in the later stages of H. pylori infection to achieve safe and effective chemoprevention of gastric adenocarcinoma.