cell surface

CXCR4: A new drug target in lung cancer

EurekAlert! - Cancer  Wed, 04/28/2010 - 22:00

(European Society for Medical Oncology) Lung cancer patients whose tumors over-express a cell surface molecule called CXCR4 do significantly worse than those who do not, Canadian researchers have found


 

Human cells secrete cancer-killing protein, UK study finds

EurekAlert! - Cancer  Wed, 07/22/2009 - 22:00

(University of Kentucky) The tumor-suppressor protein Par-4 is secreted by human and rodent cells and activates a novel extrinsic pathway involving cell surface GRP78 receptor for induction of apoptosis, researchers at the University of Kentucky led by Vivek Rangnekar announced in Cell.