(Wiley-Blackwell) New research suggests African-Americans have a higher burden of multiple, large-joint osteoarthritis (OA), and may not be recognized based on the current definition of "generalized OA." African-Americans were also more likely to have knee OA, but less likely to be affected by hand OA than Caucasians according to the findings reported today in Arthritis & Rheumatism, a peer-reviewed journal of the American College of Rheumatology.