cancer gene

(St. Jude Children's Research Hospital) The most comprehensive analysis yet of the genetic imbalances at the heart of childhood brain tumors known as high-grade gliomas identified a cancer gene that is unusually active in some tumors and is now the focus of a St.

Jude Children's Research Hospital clinical trial.

This is a story about how three sisters diagnosed with breast cancer decided to take back their lives and about the shadow the gene mutation still casts over their six kids - including five girls who all have a 50% chance of being carriers.

(California Institute of Technology) A Caltech-led team of researchers and clinicians has published the first proof that a targeted nanoparticle -- used as an experimental therapeutic and injected directly into a patient's bloodstream -- can traffic into tumors, deliver double-stranded small interfering RNAs, and turn off an important cancer gene using a mechanism known as RNA interference.

Moreover, the team provided the first demonstration that this new type of therapy can make its way to human tumors in a dose-dependent fashion.