Molecule plays early role in nonsmoking lung cancer

Courtesy EurekAlert! - Cancer  Sun, 07/26/2009 - 22:00

(Ohio State University Medical Center) A study led by Ohio State University Comprehensive Cancer Center and National Cancer Institute researchers suggests that a molecule called miR-21 is important in the development of lung cancer in never-smokers and in smokers.

Lung tumors from never-smokers with mutations in a gene called EGFR had particularly high levels of the molecule.

The findings may lead to improve targeted therapy for lung cancer, including tumors resistant to targeted drugs such as gefitinib.

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