Mice regain ability to extend telomeres suggesting potential for...

Courtesy EurekAlert! - Medicine and Health  Sun, 10/18/2009 - 22:00

(The Company of Biologists) A new study published in Disease Models and Mechanisms, reveals that mice used as a model for the human genetic disease dyskeratosis congenita, have short telomeres for 10 generations when they are interbred.

In later generations, the mice regain the ability to lengthen telomeres. Discovering how to induce this equilibration process in DKC patients could suggest new treatment strategies to decrease the genomic instability in their high turnover tissues.

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