Low forms of cyclin E reduce breast cancer drug's effectiveness

Courtesy EurekAlert! - Cancer  Mon, 02/08/2010 - 23:00

(University of Texas M. D. Anderson Cancer Center) Overexpression of low-molecular-weight (LMW-E) forms of the protein cyclin E renders the aromatase inhibitor letrozole ineffective among women with estrogen-receptor-positive (ER+) breast cancers, researchers from the University of Texas M.

D. Anderson Cancer Center report in Clinical Cancer Research.


 

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