Lack of CHFR gene expression sets stage for breast cancer

Courtesy EurekAlert! - Medicine and Health  Wed, 06/18/2008 - 23:00

(University of Michigan Health System) University of Michigan scientists have identified key steps in breast-tissue cell division that go awry when CHFR's action is low or absent.

The gene's expression is missing in more than a third of breast cancers. The findings could make it possible to identify which patients are more likely to benefit from taxanes, a class of widely used cancer drugs which includes paclitaxel and docetaxel.

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