HIV researchers solve key puzzle after 20 years of trying

Courtesy EurekAlert! - Medicine and Health  Sat, 01/30/2010 - 23:00

(Imperial College London) Researchers have made a breakthrough in HIV research that had eluded scientists for over 20 years, potentially leading to better treatments for HIV, in a study published today in the journal Nature.

The researchers, from Imperial College London and Harvard University, have grown a crystal that reveals the structure of an enzyme called integrase, which is found in retroviruses like HIV.

When HIV infects someone, it uses integrase to paste a copy of its genetic information into their DNA.

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