Case Western Reserve researchers' new pathway discovery publishe...

Courtesy EurekAlert! - Medicine and Health  Thu, 12/03/2009 - 23:00

(Case Western Reserve University) Case Western Reserve University researchers, from the School of Medicine's Department of Nutrition, discovered two new metabolic pathways by which products of lipid peroxidation and some drugs of abuse, known as 4-hydroxyacids, are metabolized.

The pathways were identified by a combination of metabolomics and mass isotopomer analysis. The findings shed new light on the mechanism of action of the drug of abuse gamma-hydroxybutyrate, also known as "the date rape drug."

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